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Recurrent Diarrhoeal Disease is a Major Cause of Childhood Malnutrition and Necessity of Contravention of the Vicious Cycle of Diarrhoea Related Malnutrition in Bangladesh

Received: 24 September 2023     Accepted: 13 October 2023     Published: 24 November 2023
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Abstract

In children, diarrheal illness and its sequelae continue to be a leading cause of morbidity and death, particularly in impoverished nations like Bangladesh. Globally, diarrheal illnesses pose a severe threat to public health, particularly because they are the second-leading cause of mortality in children (behind respiratory illnesses). About 63% of the worldwide burden of childhood diarrhea affects children under the age of five. The etiology of many disorders must be accurately and quickly detected, but standard procedures are typically unsuccessful in doing so, in addition to being time- and labor-intensive. Up to 40% of cases of diarrhoea, on average, have an unknown etiological cause. This study highlights the promise of the metagenomics technology as a diagnostic method for enteric diseases and provides an overview of current trends in the epidemiology and management of diarrhea. Increased frequency, increased volume, and altered stoma consistency are all signs of diarrhea. Environments in the industrialized and underdeveloped worlds have different pathogens. The most significant aetiological factor associated with severe dehydrating diarrhea is rotavirus diarrhea. In order to target the right treatment, it is crucial to identify the specific microbiological cause of diarrhoea. However, the World Health Organization (WHO)'s recommendations for broader preventive measures highlight the key causes of the enormous disease burden in developing nations. Worldwide, acute diarrheal illness in children under the age of five continues to be a leading cause of morbidity and death. Children are more likely to experience severe infectious diarrhea in environments with low sanitation and hygiene, limited water supply, and a lack of resources. A complete history and physical examination, as well as assessments of the child's nutritional and hydration status as well as a thorough clinical evaluation for any complications or accompanying diseases, are all necessary for the care of a kid who presents with severe diarrhea. In Bangladesh, the use of zinc supplements, reduced-osmolarity oral rehydration solution (ORS), and rotavirus vaccination are recent advancements in the management of severe diarrheal illness.

Published in International Journal of Gastroenterology (Volume 7, Issue 2)
DOI 10.11648/j.ijg.20230702.15
Page(s) 64-76
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2023. Published by Science Publishing Group

Keywords

Infectious Diarrhea, Dehydration, Developing Countries, Diarrheal Disease, Nutritional Status, Under-5 Children, Gastrointestinal Diseases, Gastroenteritis

References
[1] UNICEF. One is Too Many: Ending child deaths from pneumonia and diarrhoea [Internet]. UNICEF DATA. 2016 [cited 2022 Sep 26]. Available from: https://data.unicef.org/resources/one-many-ending-child-deathspneumonia-
[2] diarrhoea/Bern C, Martines J, De Zoysa I, Glass RI. The magnitude of the global problem of diarrhoeal disease: a ten-year update. Bulletin of the world health organization. 1992; 70 (6): 705.
[3] Bangladesh Bureau of Statistics [2016]: Report on Bangladesh Sample Vital Statistics 2016. Reproduction, Documentation & Publication Section (RDP). Data Extract. [2017]. Available from: http://www.bbs.gov.bd/
[4] Das S, Gulshan J. Different forms of malnutrition among under five children in Bangladesh: a cross sectional study on prevalence and determinants. Bmc Nutrition. 2017 Dec; 3 (1): 1-2.
[5] Guerrant RL, Oriá RB, Moore SR, Oriá MO, Lima AA. Malnutrition as an enteric infectious disease with long-term effects on child development. Nutrition reviews. 2008 Sep 1; 66 (9): 487-505.
[6] Molla A, Molla AM, Sarker SA, Khatun M. Whole-gut transit time and its relationship to absorption of macronutrients during diarrhoea and after recovery. Scandinavian journal of gastroenterology. 1983 May 1; 18 (4): 537- 43.
[7] Brown KH. Diarrhea and malnutrition. J Nutr. 2003 Jan; 133 (1): 328S-332S. doi: 10.1093/jn/133.1.328S. PMID: 12514320.
[8] Roy SK, Buis M, Weersma R, Khatun W, Chowdhury S, Begum A, Sarker D, Thakur SK, Khanam M. Risk factors of mortality in severely-malnourished children hospitalized with diarrhoea. Journal of health, population, and nutrition. 2011 Jun; 29 (3): 229.
[9] Guerrant RL, Schorling JB, Mc Auliffe JF, De Souza MA. Diarrhea as a cause and an effect of malnutrition: diarrhea prevents catch-up growth and malnutrition increases diarrhea frequency and duration. The American journal of tropical medicine and hygiene. 1992 Jul 1; 47 (1 Pt 2): 28-35.
[10] Ho FK, Rao N, Tung KTS, Wong RS, Wong WHS, Tung JYL, Chua GT, Tso WWY, Bacon-Shone J, Wong ICK, Yousafzai A, Wright C, Ip P. Association of Early Nutritional Status With Child Development in the Asia Pacific Region. JAMA Netw Open. 2021 Dec 1; 4 (12): e2139543. doi: 10.1001/jamanetworkopen.2021.39543. PMID: 34913975; PMCID: PMC8678697.
[11] Guarino A, Albano F, Ashkenazi S, et al. European Society for Paediatric Gastroenterology, hepatology and Nutrition/European Society for paediatric Infectious Diseases Evidence-based Guidelines for the Management of Acute Gastroenteritis in Children in Europe. JPGN 2008; 46: S81–S122.
[12] Elliott EJ. Acute Gastroenteritis in Children. BMJ 2007; 334: 35–40.
[13] Gracey M. Diarrhoeal disease and malnutrition. Churchill Livingstone, Edinburgh, 1985.
[14] Gracey M. Diarrhea and Malnutrition: A Challenge for Pediatricians. J Pediatr Gastroenterol Nutr; 1996, 22 (1): 6-16.
[15] Jensen PK, Jayasinghe G, van der Hoek W, Cairncross S, Dalsgaard A. Is there an association between bacteriological drinking water quality and childhood diarrhea in developing countries? Trop Med Int Health; 2004; 9 (11): 1210–15.
[16] Jensen PK, Ensink JH, Jayasinghe G, van der Hoek W, Cairncross S, Dalsgaard A. Domestic transmission routes of pathogens: the problem of in-house contamination of drinking water during storage in developing countries. Trop Med Int Health; 2002; 7 (7): 604–9.
[17] Curtis V, Cairncross S, Yonli R. Review: Domestic hygiene and diarrhoea –pinpointing the problem. Trop Med Int Health; 2000; 5 (1): 22–3.
[18] Jane SH, Swanson LN. Diarrhea. A Jobson Publication, Available from URL: http://www.uspharmacist.com
[19] Kosek M, Bern C, Guerrant RL. The global burden of diarrhoeal disease, as estimated from studies published between 1992 and 2000. Bull World Health Organ 2003; 81 (3): 197-204.
[20] Vesikari T and Torun B. Diarrheal Diseases. In: Kari SL, Staffan B, Makela PH, Miikka P, editors. Health and Disease in developing countries. Macmillan Education Ltd. London and Oxford, 1994. p. 136-46.
[21] Banerjee B, Hazra S, Bandyopadhyay D. Diarrhea Management Among Under Fives. Institute of Hygiene and Public Health, India, 2003.
[22] Molbak K. The epidemiology of diarrheal diseases in early childhood: A review of community studies in Guinea-Bissau. University of Copenhaghen, 2000.
[23] Abram SB, editor. Control of Communicable diseases Manual. 16th ed. Am Public Health Assoc. 1995: 250-4.
[24] Waldman R, Fontaine O, Richard L. Epidemic dysentery. A supplement to Dialogue on Diarrhoea. Published by AHRTAG, UK. 1994.
[25] WHO. Department of Child and Adolescent Health and Development. The evolution of diarrheal and acute respiratory diseases control at WHO. World Health Organ. 1999.
[26] Armon K, Stephenson T, MacFaul R, Eccleston P, Werneke U. An evidence and consensus based guideline for acute diarrhoea management. Arch Dis Child; 2001; 85: 132-42.
[27] Woldemicael G. Diarrheal morbidity among children in Eritrea: environmental and socio-economic determinants. J Health Popul Nutr; 2001; 19 (2): 83-90.
[28] Yassin K. Morbidity and risk factors of diarrheal disease among under-five children in rural upper Egypt. J Trop Pediatr; 2000; 46 (5): 282-7.
[29] Teklemariam S, Getaneh T, Bekele F. Environmental determinants of diarrheal morbidity in under-five children, Keffa-Sheka zone, south west Ethiopia. Ethiop Med J; 2000; 38 (1): 27-34.
[30] Karim AS, Akhter S, Rahman MA, Nazir MF. Risk factors of persistent diarrhea in children below five years of age. Indian J Gastroenterol. 2001; 20 (2): 59-61.
[31] Jinadu MK, Olusi SO, Agun JI, Fabiyi AK. Childhood diarrhoea in rural Nigeria. I. Studies on prevalence, mortality and socio-environmental factors. J Diarrhoeal Dis Res. 1991; 9 (4): 323-7.
[32] Marjatta BS. Water supply and diarrhea in East African community. A case control study on the quality of water supplies and the occurrence of diarrhea among small children in a rural area of Western Kenya. University of Oulu Printing Center, 1994: 37-57.
[33] Etiler N, Velipasaoglu S, Aktekin M. Risk factors for overall and persistent diarrhea in infancy in Antalya, Turkey. Public Health, 2004; 118 (1): 62-9.
[34] Gascon J, Vargas M, Schellenberg D, Urassa H, Casals C, Kahigva E, Aponte JJ, Mshinda H, Vila J. Diarrhea in Children under 5 Years of Age from Ifakara, Tanzania. J Clin Microbiol. 2000; 38 (12): 4459–62.
[35] Molbak K, Jensen H, Ingholt L, Aaby P. Risk factors for diarrheal disease incidence in early childhood: a community cohort study from Guinea-Bissau. Am J Epidemiol. 1997; 146 (3): 273-82.
[36] Wijewardene K, Fonseka P, Wijayasiri WA. Risk factors contributing to acute diarrhoeal disease in children below five years. Ceylon Med J, 1992; 37 (4): 116-9.
[37] Tumwine JK, Thompson J, Katua-Katua M, Mujwajuzi M, Johnstone N, Porras I. Diarrhoea and effects of different water sources, sanitation and hygiene behaviour in E ast Africa. Trop Med Int Health. 2002; 7 (9): 750-6.
[38] Brooks JT et al. Epidemiology of sporadic bloody diarrhea in rural western, Kenya. Am J Trop Med Hyg. 2003; 68 (6): 671–7.
[39] Ghosh S, Sengupta PG, Mondal SK, Banu MK, Gupta DN, Sircar BK. Risk behavioural practices of rural mothers as determinants of childhood diarrhoea. J Commun Dis. 1997; 29 (1): 7-14.
[40] Aulia H, Surapaty SC, Bahar E, Susanto TA, Roisuddin, Hamzah M, Ismail R. Personal and domestic hygiene and its relationship to the incidence of diarrhoea in south Sumatera. J Diarrhoeal Dis Res. 1994; 12 (1): 42-8.
[41] Gorter AC, Sandiford P, Pauw J, Morales P, Perez RM, Alberts H. Hygiene behaviour in rural Nicaragua in relation to diarrhoea. Int J Epidemiol. 1998; 27 (6): 1090-100.
[42] Curtis V, Cairncross S, Yonli R. Review: Domestic hygiene and diarrhoea – pinpointing the problem. Trop Med Int Health; 2000; 5 (1): 26–30.
[43] Long K, Vasquez-Garibay E, Mathewson J, de la Cabada J, DuPont H. The impact of infant feeding patterns on infection and diarrheal disease due to enterotoxigenic Escherichia Coli. Salud Publica Mex. 1999; 41 (4): 263-70.
[44] VanDerslice J, Popkin B, Briscoe J. Drinking-water quality, sanitation, and breast feeding: their interactive effects on infant health. Bull World Health Organ. 1994; 72 (4): 589-601.
[45] Public Health News Center. Johns Hopkins University. Exclusive Breastfeeding Training For Mothers Helps Reduce Diarrheal Disease Among Infants. The University. 2005.
[46] Yudith Setiati Ermaya, Dwi Prasetyo, Iesje Martiza Sabaroedin, Yati Soenarto: A Correlational study between Nutritional Status and Severity of Rotavirus Diarrhea in children under five years in Bandung, Indonesia, Journal of Gastroenterology and Hepatology Research, Vol 6, No 6 (2017).
[47] Rice AL, Sacco L, Hyder A, Black RE. Malnutrition as an underlying cause of childhood deaths associated with infectious diseases in developing countries. Bull World Health Organ. 2000; 78 (10): 1207-21.
[48] National Medical Society, USA. Diarrhea in HIV-Infected Patients. Available from URL: http://www.medical-library.org/
[49] Adkins HJ, Escamilla J, Santiago LT, Ranoa C, Echeverria P, Cross JH. Two-year survey of etiologic agents of diarrheal disease at San Lazaro Hospital, Manila, Philippines. Republic of the J Clin Microbiol. 1987; 25 (7): 1143–7.
[50] Henry FS, Patwary Y, Huttly SR, Aziz KM. Bacterial contamination of weaning, foods and drinking water in rural Bangladesh. Epidemiol Infect. 1990; 104 (1): 79-85.
[51] Pinfold JV, Horan NJ, Mara DD. Seasonal effects on the reported incidence of acute diarrhoeal disease in northeast Thailand. Int J Epidemiol. 1991; 20 (3): 777-86.
[52] Teshima A et al. Climate impact on seasonal patterns of diarrhea diseases in Tropical area. University of Kyoto, Japan, 2004.
[53] Anwar MY, Warren JL, Pitzer VE. Diarrhea Patterns and Climate: A Spatiotemporal Bayesian Hierarchical Analysis of Diarrheal Disease in Afghanistan. Am J Trop Med Hyg. 2019 Sep; 101 (3): 525-533. doi: 10.4269/ajtmh.18-0735. PMID: 31392940; PMCID: PMC6726951.
[54] Protection of the Human Environment - Task Force on Climate and Health. El Nino and Health. WHO, Geneva, 1999, 22-23.
[55] Pascual M, Rodo X, Ellner SP, Colwell R, Bouma MJ. Cholera Dynamics and El Nino-Southern Oscillation. Science. 2000; 289 (5485): 1766-9.
[56] Institute of One World Health. Diarrheal disease Fact Sheet. 2000. Available from URL: http://www.oneworldhealth.org
[57] Parashar UD, Bresee JS, Glass RI. The global burden of diarrhoeal disease in children. Bull World Health Organ 2003; 81 (4): 236.
[58] Environmental Health Project. Diarrhea Prevention. Lessons Learned. 1999. Available from URL: http://www.ehproject.org/PDF/Lessons_Learned
[59] Keusch GT, Fontaine O, Bhargava A, et al. Diarrheal Diseases. In Jamison D, Measham R, Claeson M, editors. Disease Control Priorities in Developing Countries, 2nd ed. Washington: World Bank 2006.
[60] Niehaus MD, Moore SR, Patrick PD, et al. Early childhood diarrhea is associated with diminished cognitive function 4 to 7 years later in children in a northeast Brazilian shantytown. Am J Trop Med Hyg 2002; 66 (5): 590-3.
[61] McQuaid KR. Gastrointestinal Disorders. In: McPhee S, Papadakis M, Tierney LJ, Eds. Current Medical Diagnosis & Treatment 2009.
[62] Donnenberg MS, Kaper JB. Enteropathogenic Escherichia coli. Infect Immun 1992; 60 (10): 3953-61.
[63] Ochoa TJ, Salazar-Lindo E, Cleary TG. Management of children with infection-associated persistent diarrhea. Semin Pediatr Infect Dis 2004; 15 (4): 229-36.
[64] Jill W. Ahs, Wenjing Tao, Jenny Löfgren and Birger C. Forsberg: Diarrheal Diseases in Low- and Middle-Income Countries: Incidence, Prevention and Management, The Open Infectious Diseases Journal, 2010, 4, 113-124.
[65] Geldsetzer P, Williams TC, Kirolos A, Mitchell S, Ratcliffe LA, Kohli-Lynch MK, Bischoff EJ, Cameron S, Campbell H. The recognition of and care seeking behaviour for childhood illness in developing countries: a systematic review. PLoS One. 2014 Apr 9; 9 (4): e93427. doi: 10.1371/journal.pone.0093427. PMID: 24718483; PMCID: PMC3981715.
[66] Cheng AC, McDonald JR, Thielman NM. Infectious Diarrhoea in Developed and Developing Countries. J Clin Gastroenterol 2005; 39 (9): 757–73.
[67] Forsberg BC, Petzold MG, et al. Diarrhoea case management in low-and middle-income countries –an unfi nished agenda. Bulletin of the WHO Jan 2007, 85 (1).
[68] Cunliffe NA, Kilgore PE, Bresee JS, et al. Epidemiology of rotavirus diarrhoea in Africa: a review to assess the need for rotavirus immunization. Bulletin of the World Health Organisation 1998; 76 (5): 525–37.
[69] Bellemare S, Hartling L et al. Oral rehydration versus intravenous therapy for treating dehydration due to gastroenteritis in children: a meta-analysis of randomised controlled trials. The Cochrane Library 2006, issue 4.
[70] Stephen B. Freedman, Samina Ali, Marta Oleszczuk, Serge Gouin, Lisa Hartling: Treatment of acute gastroenteritis in children: an overview of systematic reviews of interventions commonly used in developed countries, Evidence-Based Child Health: A Cochrane Review Journal, Volume8, Issue4, July 2013, Pages 1123-1137, doi.org/10.1002/ebch.1932.
[71] Hoque KM, Binder HJ. Zinc in the Treatment of Acute Diarrhoea: Current Status and Assessment. Gastroenterol 2006; 130: 2201–5.
[72] A Meta-analysis of the Effects of Oral Zinc in the Treatment of Acute and Persistent Diarrhea. Pediatrics 2008; 121 (2): 326–36.
[73] Salvatore S, Hauser B, Devreker T, et al. Probiotics and zinc in acute infectious gastroenteritis in children: are they effective? Nutrition 2007; 23: 498–506.
[74] Wittenberg DF ed. Gastrointestinal Disorders in Coovadia’s Paediatrics and Child Health (6th edition) 2009: 501–17.
[75] Bhutta ZA, Nelson EA, Lee WS, et al. Recent Advances and Evidence Gaps in Persistent Diarrhea. JPGN, 2008; 47: 260–5.
Cite This Article
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    Istiaque Hossain, M., Delwar Hossain, M., Kumar Ghosh, S., Rahman, K., Monir Hossain, M., et al. (2023). Recurrent Diarrhoeal Disease is a Major Cause of Childhood Malnutrition and Necessity of Contravention of the Vicious Cycle of Diarrhoea Related Malnutrition in Bangladesh. International Journal of Gastroenterology, 7(2), 64-76. https://doi.org/10.11648/j.ijg.20230702.15

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    ACS Style

    Istiaque Hossain, M.; Delwar Hossain, M.; Kumar Ghosh, S.; Rahman, K.; Monir Hossain, M., et al. Recurrent Diarrhoeal Disease is a Major Cause of Childhood Malnutrition and Necessity of Contravention of the Vicious Cycle of Diarrhoea Related Malnutrition in Bangladesh. Int. J. Gastroenterol. 2023, 7(2), 64-76. doi: 10.11648/j.ijg.20230702.15

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    AMA Style

    Istiaque Hossain M, Delwar Hossain M, Kumar Ghosh S, Rahman K, Monir Hossain M, et al. Recurrent Diarrhoeal Disease is a Major Cause of Childhood Malnutrition and Necessity of Contravention of the Vicious Cycle of Diarrhoea Related Malnutrition in Bangladesh. Int J Gastroenterol. 2023;7(2):64-76. doi: 10.11648/j.ijg.20230702.15

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  • @article{10.11648/j.ijg.20230702.15,
      author = {Mohammed Istiaque Hossain and Mohammad Delwar Hossain and Susanta Kumar Ghosh and Khadija Rahman and Mohammad Monir Hossain and Afsana Khanom and Riffat Mohiuddin and Tasnim Ahmed},
      title = {Recurrent Diarrhoeal Disease is a Major Cause of Childhood Malnutrition and Necessity of Contravention of the Vicious Cycle of Diarrhoea Related Malnutrition in Bangladesh},
      journal = {International Journal of Gastroenterology},
      volume = {7},
      number = {2},
      pages = {64-76},
      doi = {10.11648/j.ijg.20230702.15},
      url = {https://doi.org/10.11648/j.ijg.20230702.15},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijg.20230702.15},
      abstract = {In children, diarrheal illness and its sequelae continue to be a leading cause of morbidity and death, particularly in impoverished nations like Bangladesh. Globally, diarrheal illnesses pose a severe threat to public health, particularly because they are the second-leading cause of mortality in children (behind respiratory illnesses). About 63% of the worldwide burden of childhood diarrhea affects children under the age of five. The etiology of many disorders must be accurately and quickly detected, but standard procedures are typically unsuccessful in doing so, in addition to being time- and labor-intensive. Up to 40% of cases of diarrhoea, on average, have an unknown etiological cause. This study highlights the promise of the metagenomics technology as a diagnostic method for enteric diseases and provides an overview of current trends in the epidemiology and management of diarrhea. Increased frequency, increased volume, and altered stoma consistency are all signs of diarrhea. Environments in the industrialized and underdeveloped worlds have different pathogens. The most significant aetiological factor associated with severe dehydrating diarrhea is rotavirus diarrhea. In order to target the right treatment, it is crucial to identify the specific microbiological cause of diarrhoea. However, the World Health Organization (WHO)'s recommendations for broader preventive measures highlight the key causes of the enormous disease burden in developing nations. Worldwide, acute diarrheal illness in children under the age of five continues to be a leading cause of morbidity and death. Children are more likely to experience severe infectious diarrhea in environments with low sanitation and hygiene, limited water supply, and a lack of resources. A complete history and physical examination, as well as assessments of the child's nutritional and hydration status as well as a thorough clinical evaluation for any complications or accompanying diseases, are all necessary for the care of a kid who presents with severe diarrhea. In Bangladesh, the use of zinc supplements, reduced-osmolarity oral rehydration solution (ORS), and rotavirus vaccination are recent advancements in the management of severe diarrheal illness.
    },
     year = {2023}
    }
    

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    T1  - Recurrent Diarrhoeal Disease is a Major Cause of Childhood Malnutrition and Necessity of Contravention of the Vicious Cycle of Diarrhoea Related Malnutrition in Bangladesh
    AU  - Mohammed Istiaque Hossain
    AU  - Mohammad Delwar Hossain
    AU  - Susanta Kumar Ghosh
    AU  - Khadija Rahman
    AU  - Mohammad Monir Hossain
    AU  - Afsana Khanom
    AU  - Riffat Mohiuddin
    AU  - Tasnim Ahmed
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    DO  - 10.11648/j.ijg.20230702.15
    T2  - International Journal of Gastroenterology
    JF  - International Journal of Gastroenterology
    JO  - International Journal of Gastroenterology
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    PB  - Science Publishing Group
    SN  - 2640-169X
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    AB  - In children, diarrheal illness and its sequelae continue to be a leading cause of morbidity and death, particularly in impoverished nations like Bangladesh. Globally, diarrheal illnesses pose a severe threat to public health, particularly because they are the second-leading cause of mortality in children (behind respiratory illnesses). About 63% of the worldwide burden of childhood diarrhea affects children under the age of five. The etiology of many disorders must be accurately and quickly detected, but standard procedures are typically unsuccessful in doing so, in addition to being time- and labor-intensive. Up to 40% of cases of diarrhoea, on average, have an unknown etiological cause. This study highlights the promise of the metagenomics technology as a diagnostic method for enteric diseases and provides an overview of current trends in the epidemiology and management of diarrhea. Increased frequency, increased volume, and altered stoma consistency are all signs of diarrhea. Environments in the industrialized and underdeveloped worlds have different pathogens. The most significant aetiological factor associated with severe dehydrating diarrhea is rotavirus diarrhea. In order to target the right treatment, it is crucial to identify the specific microbiological cause of diarrhoea. However, the World Health Organization (WHO)'s recommendations for broader preventive measures highlight the key causes of the enormous disease burden in developing nations. Worldwide, acute diarrheal illness in children under the age of five continues to be a leading cause of morbidity and death. Children are more likely to experience severe infectious diarrhea in environments with low sanitation and hygiene, limited water supply, and a lack of resources. A complete history and physical examination, as well as assessments of the child's nutritional and hydration status as well as a thorough clinical evaluation for any complications or accompanying diseases, are all necessary for the care of a kid who presents with severe diarrhea. In Bangladesh, the use of zinc supplements, reduced-osmolarity oral rehydration solution (ORS), and rotavirus vaccination are recent advancements in the management of severe diarrheal illness.
    
    VL  - 7
    IS  - 2
    ER  - 

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Author Information
  • Department of Paediatrics, Evercare Hospital, Dhaka, Bangladesh

  • Department of Paediatrics, United Medical College Hospital, Dhaka, Bangladesh

  • Department of Pediatrics, Nibedita Shishu Consultation Center, Dhaka, Bangladesh

  • Department of Pediatrics, Dr. MR Khan Shishu Hospital & ICH, Dhaka, Bangladesh

  • Department of Paediatric, Ibnsina Diagnostic & Consultation Centre, Dhaka, Bangladesh

  • Department of Paediatric, Sajida Hospital, Dhaka, Bangladesh

  • Department of Paediatric, Addin Medical College Hospital, Dhaka, Bangladesh

  • Department of Paediatric, Addin Medical College Hospital, Dhaka, Bangladesh

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